Mavacamten Applying this medicine with any of the subsequent medicines will likely be not advisable, but might be necessary in some instances. If equally medicines are prescribed with each other, your health care provider may possibly alter the dose or how often you employ one particular or equally of the medicines.
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Keep track of Intently (1)modafinil boosts amounts of eluxadoline by affecting hepatic enzyme CYP2C19 metabolism. Use Warning/Keep track of. For a precautionary measure due to incomplete info on the metabolism of eluxadoline, use caution when coadministered with potent CYP2C19 inhibitors.
nefazodone will improve the degree or outcome of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
Stay clear of coadministration of ganaxolone with reasonable or potent CYP3A4 inducers. If coadministration unavoidable, take into account growing ganaxolone dose; having said that, usually do not exceed maximum day-to-day dose for weight.
Employing Alcoholic beverages or tobacco with certain medicines might also trigger interactions to happen. Talk about using your healthcare Specialist the usage of your medication with food items, alcohol, or tobacco.
etravirine will reduce the extent or influence of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
Sufferers ought to be encouraged to talk to their healthcare supplier immediately when they encounter a rash or any allergic reaction, depression, panic, or signs of psychosis or mania.
crofelemer boosts amounts of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of. Crofelemer has the likely to inhibit CYP3A4 at concentrations predicted from the gut; unlikely to inhibit systemically since minimally absorbed.
Keep track of Carefully (1)levoketoconazole will increase the amount or website outcome of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
Other medication could connect with modafinil, like prescription and in excess of-the-counter medicines, nutritional vitamins, and herbal solutions. Notify Each individual within your health care providers about all medicines you use now and any medicine you start or stop using.
Allergic reactions which include rash, angioedema, anaphylaxis, and Stevens–Johnson syndrome could be activated by an immunological response to modafinil or its metabolites.
efavirenz will decrease the extent or influence of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
modafinil will increase the level or result of lansoprazole by impacting hepatic enzyme CYP2C19 metabolism. Minimal/Importance Not known. Net effect on pantoprazole actions unidentified on account of opposing outcomes of CYP450 enzymes; watch